A scorpion native to Eastern Mexico might have more than mere toxin in its sting. Researchers at Stanford University and in Mexico have discovered that the venom further contains two color-changing compounds that would support to combat bacterial infections.
The team not only removed the compounds within the scorpion’s venom but also formed them in the lab and validated that the lab-made versions killed staphylococcus and drug-resistant tuberculosis microorganism in tissue samples and mice.
The findings, printed in the June 10 issue of the magazine Proceedings of the National Academy of Sciences, spotlight the possible pharmacological treasures looking forward a discovery within the pollutants of scorpions, snakes, snails, and different toxic creatures.
“By quantity, scorpion venom is likely one of the most precious things on the planet. It could price $39 million to supply a gallon of it,” said a senior research writer Richard Zare, who led the Stanford team. “For those who depended best on scorpions to produce it, no one could afford it, so you must determine what the essential ingredients are and be capable of synthesizing them.”
Zare worked along with his colleagues in Mexico and Lourival Possani, a professor of molecular medicine at the National School of Mexico, whose scholars caught specimens of the scorpion Diplocentrus melici for research.
“The choice of this species of scorpion is tricky because, during the winter and dry seasons, the scorpion is hidden,” Possani stated. “We will only find it during the rainy season.”
For the past 45 years, Possani has aimed to identify compounds with pharmacological power in scorpion venom. His team, before, exposed effective antibiotics, pesticides and anti-malarial agents hidden within the arachnid’s poison.